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Dietary Fructose Causes Liver Damage in Animal Model, Study Finds
Researchers found that over a six-week period, liver damage more than doubled in animals fed a high-fructose diet as compared to those in the control group. The study was published in the online edition of the American Journal of Clinical Nutrition.
“Is a calorie a calorie? Are they all created equal? Based on this study, we would say not,” said Kylie Kavanagh, DVM, assistant professor of pathology-comparative medicine and lead author of the study.
The big question for researchers who conducted similar animal studies in the past was whether the animals suffered liver damage because of weight gain from eating too much or from some other cause. To answer that question, this study was designed to prevent weight gain.
“What surprised us the most was how quickly the liver was affected and how extensive the damage was, especially without weight gain as a factor,” Kavanagh said.
Kavanagh said the study could have clinical implications because most doctors and scientists have thought that it was the fat in and around tissues in the body that causes health problems.
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